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| Cat. Number | T 98475 |
| Chemical Name | T 98475 |
| CAS Number | [192887-28-8] |
| Mol. Formula | C37H37F2N3O4S |
| Mol. Weight | 657.77 |
| Qty 1 |
1mg |
| Synonym | 7-[(2,6-Difluorophenyl)methyl]-4,7- dihydro-2-[4-[(2-methyl-1-oxopropyl)amino]phenyl]- 3-[[methyl(phenylmethyl)amino]methyl]-4-oxo-thieno [2,3-b]pyridine-5-carboxylic acid 1-methylethyl ester |
| Solubility | Soluble to 50 mM in DMSO |
| Storage condition | Desiccate at +4°C |
| References | Potent, orally active and non-peptide gonadotropin-releasing hormone (GnRH, LHRH) receptor antagonist (IC50 values are 0.2, 4.0 and 60 nM for human, monkey and rat GnRH receptors respectively). Inhibits LH release in vitro (IC50 = 100 nM) and reduces plasma LH concentration in castrated male cynomolgus monkeys. Purity: >98 % |
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