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/ Products Classification 点击展开+Cat. Number | UBP 310 |
Chemical Name | UBP 310 |
Mol. Formula | C14H15N3O6S |
Mol. Weight | 353.35 |
Qty 1 |
10mg |
Qty 2 | 50mg |
Synonym | (S)-1-(2-Amino-2-carboxyethyl)-3-(2 -carboxy-thiophene-3-yl-methyl)-5-methylpyrimidine -2,4-dione |
Solubility | Soluble to 100 mM in DMSO |
Storage condition | Store at +4°C |
References | GLUK5 kainate receptor antagonist (IC50 = 130 nM); also blocks recombinant homomeric GLUK7 receptors. Displays 12,700-fold selectivity for GLUK5 over GLUK6. Exhibits no activity at mGlu group I or NMDA receptors at concentrations of up to 10 μM. Apparent KD value is 18 ± 4 nM for depression of kainate responses on the dorsal root. Purity: >98 % |