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Cat. Number
UBP 310
Chemical Name
UBP 310
Mol. Formula
C14H15N3O6S
Mol. Weight
353.35
Qty 1
10mg
Qty 2
50mg
Synonym
(S)-1-(2-Amino-2-carboxyethyl)-3-(2 -carboxy-thiophene-3-yl-methyl)-5-methylpyrimidine -2,4-dione
Solubility
Soluble to 100 mM in DMSO
Storage condition
Store at +4°C
References
GLUK5 kainate receptor antagonist (IC50 = 130 nM); also blocks recombinant homomeric GLUK7 receptors. Displays 12,700-fold selectivity for GLUK5 over GLUK6. Exhibits no activity at mGlu group I or NMDA receptors at concentrations of up to 10 μM. Apparent KD value is 18 ± 4 nM for depression of kainate responses on the dorsal root.
Purity: >98 %
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