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Cat. Number
UBP 296
Chemical Name
UBP 296
Mol. Formula
C15H15N3O6
Mol. Weight
333.3
Qty 1
10mg
Qty 2
50mg
Synonym
(RS)-1-(2-Amino-2-carboxyethyl)-3-( 2-carboxybenzyl)pyrimidine-2,4-dione
Solubility
Soluble to 10 mM in 1eq. NaOH and to 10 mM in DMSO
Storage condition
Store at RT
References
Selective and potent GluR5-subunit containing kainate receptor antagonist (apparent KD = 1.09 mM). Displays ~ 90-fold selectivity over AMPA receptors and recombinant human GluR6- and KA2-containing kainate receptors. Has little or no action at NMDA or group I mGlu receptors. Selectively blocks kainate receptor-mediated LTP induction in rat hippocampal mossy fibres.
Purity: >98 %
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