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Cat. Number
Valinomycin
Chemical Name
Valinomycin
CAS Number
[2001-95-8]
Mol. Formula
C54H90N6O18
Mol. Weight
1111.32
Qty 1
10mg
Qty 2
50mg
Synonym
Cyclo(D-α-hydroxyisovaleryl-D-valyl- L-lactoyl-L-valyl-D-α-hydroxyisovaleryl-D-valyl-L-l actoyl-L-valyl-D-α-hydroxyisovaleryl-D-valyl-L-lact oyl-L-valyl)
Solubility
Soluble to 25 mM in DMSO and to 25 mM in ethanol
Storage condition
Desiccate at -20°C
References
Selective K+ ionophore (K0.5 values are 48, 73, 75, 93 and 246 mM for K+, Rb+, Cs+, Na+ and Li+ respectively) that transports K+ across biological and artificial lipid membranes. Inhibits Ca2+-ATPase activity and induces apoptosis through mitochondrial membrane depolarization, caspase-3 activation and phosphatidylserine translocation in vitro.
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