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| Cat. Number | XR 9051 HCl |
| Chemical Name | XR 9051 HCl |
| CAS Number | [180422-22-4] |
| Mol. Formula | C39H36N4O5.HCl |
| Mol. Weight | 679.2 |
| Qty 1 |
10mg |
| Qty 2 | 50mg |
| Synonym | N-[4-[2-(3,4-Dihydro-6,7-dimethoxy- 2(1H)-isoquinolinyl)ethyl]phenyl]-3-[(Z)-[(5Z)-4-m ethyl-3,6-dioxo-5-(phenylmethylene)piperazinyliden e]methyl]benzamide hydrochloride |
| Solubility | Soluble to 100 mM in DMSO |
| Storage condition | Store at -20°C |
| References | Potent modulator of P-glycoprotein-mediated multidrug resistance (MDR) that inhibits the binding of cytotoxics to P-glycoprotein (EC50 = 134 nM). Reverses resistance to a variety of cytotoxic drugs (including doxorubicin, etoposide and vincristine) in several murine and human P-gp-overexpressing cell lines. Orally active. Purity: >98 % |
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