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| Cat. Number | XE 991 dihydrochloride |
| Chemical Name | XE 991 dihydrochloride |
| CAS Number | [122955-42-4] |
| Mol. Formula | C26H20N2O.2HCl |
| Mol. Weight | 449.37 |
| Qty 1 |
10mg |
| Qty 2 | 50mg |
| Synonym | 10,10-bis(4-Pyridinylmethyl)-9(10H) -anthracenone dihydrochloride |
| Solubility | Soluble to 100 mM in water |
| Storage condition | Desiccate at RT |
| References | Potent and selective blocker of KCNQ voltage-gated potassium channels. Blocks KCNQ2+3/M-currents (IC50 = 0.6 - 0.98 μM) and KCNQ1 homomeric channels (IC50 = 0.75 μM) but is less potent against KCNQ1/minK channels (IC50 = 11.1 μM). Augments hippocampal ACh release and is a cognitive enhancer following oral administration in vivo. Purity: >99 % |
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