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| Cat. Number | XCT 790 |
| Chemical Name | XCT 790 |
| CAS Number | [725247-18-7] |
| Mol. Formula | C23H13F9N4O3S |
| Mol. Weight | 596.42 |
| Qty 1 |
10mg |
| Qty 2 | 50mg |
| Synonym | 3-[4-(2,4-Bis-trifluoromethylbenzyl oxy)-3-methoxyphenyl]-2-cyano-N-(5-trifluoromethyl -1,3,4-thiadiazol-2-yl)acrylamide |
| Solubility | Soluble to 25 mM in DMSO |
| Storage condition | Store at +4°C |
| References | Selective ERRα antagonist/inverse agonist (IC50 = ~400 nM). Displays no antagonist activity at ERRγ or ERα at concentrations below 10 μM. Interferes with PPARγ coactivator-1α (PGC-1α)/ERRα-dependent signaling: inhibits PGC-1α induction of ERRα and MAO-B gene expression and downregulates the constitutive transcriptional activity of ERRα in numerous cell lines. Purity: >99 % |
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