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| Cat. Number | YM 90709 |
| Chemical Name | YM 90709 |
| CAS Number | [163769-88-8] |
| Mol. Formula | C22H21N3O2 |
| Mol. Weight | 359.43 |
| Qty 1 |
10mg |
| Synonym | 5,6-Dihydro-2,3-dimethoxy-6,6-dimet hylbenz[7,8]indolizino[2,3-b]quinoxaline |
| Solubility | Soluble to 25 mM in ethanol and to 50 mM in DMSO |
| Storage condition | Store at RT |
| References | Novel, selective inhibitor of interleukin-5 (IL-5) (IC50 = 0.45 - 1 mM). Inhibits IL-5-prolonged eosinophil survival and IL-5-induced tyrosine phosphorylation of JAK2 without inhibiting GM-CSF-mediated effects. Inhibits antigen-induced eosinophil and lymphocyte recruitment in rat airways in vivo, without affecting peripheral blood or bone marrow leukocytes. Purity: >99 % |
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