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Cat. Number
YM 511
Chemical Name
YM 511
CAS Number
[148869-05-0]
Mol. Formula
C16H12BrN5
Mol. Weight
354.2
Qty 1
10mg
Qty 2
50mg
Synonym
4-[[(4-Bromophenyl)methyl]-4H-1,2,4 -triazol-4-ylamino]benzonitrile
Solubility
Soluble to 100 mM in DMSO and to 25 mM in ethanol
Storage condition
Store at RT
References
Orally active, potent aromatase (CYP19) inhibitor (IC50 values are 0.4 and 0.12 nM at rat ovary and human placenta cells respectively) that only weakly inhibits the synthesis of other steroid hormones. Reduces plasma estrogen levels into ranges induced by ovariectomy and inhibits testosterone-induced breast cancer cell growth in vitro (IC50 = 0.13 nM).
Purity: >99 %
下一个:YM 58483上一个:YM 298198 hydrochloride
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