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/ Products Classification 点击展开+Cat. Number | YM 511 |
Chemical Name | YM 511 |
CAS Number | [148869-05-0] |
Mol. Formula | C16H12BrN5 |
Mol. Weight | 354.2 |
Qty 1 |
10mg |
Qty 2 | 50mg |
Synonym | 4-[[(4-Bromophenyl)methyl]-4H-1,2,4 -triazol-4-ylamino]benzonitrile |
Solubility | Soluble to 100 mM in DMSO and to 25 mM in ethanol |
Storage condition | Store at RT |
References | Orally active, potent aromatase (CYP19) inhibitor (IC50 values are 0.4 and 0.12 nM at rat ovary and human placenta cells respectively) that only weakly inhibits the synthesis of other steroid hormones. Reduces plasma estrogen levels into ranges induced by ovariectomy and inhibits testosterone-induced breast cancer cell growth in vitro (IC50 = 0.13 nM). Purity: >99 % |
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