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| Cat. Number | YM 298198 hydrochloride |
| Chemical Name | YM 298198 hydrochloride |
| CAS Number | [748758-45-4] |
| Mol. Formula | C18H22N4OS.HCl |
| Mol. Weight | 378.92 |
| Qty 1 |
10mg |
| Qty 2 | 50mg |
| Synonym | 6-Amino-N-cyclohexyl-N,3-dimethylth iazolo[3,2-a]benzimidazole-2-carboxamide hydrochloride |
| Solubility | Soluble to 100 mM in water |
| Storage condition | Desiccate at +4°C |
| References | Non-competitive antagonist with high affinity and selectivity for mGlu1 receptors (Ki = 19 nM); inactive at other mGlu receptor subtypes (mGlu2-7), ionotropic receptors and glutamate transporters (IC50 > 10 μM). Inhibits glutamate-induced IP production more potently than CPCCOEt (IC50 values are 16 nM and 6.3 μM respectively), and is orally active in vivo, demonstrating an antinociceptive effect in hyperalgesic mice. Purity: >99 % |
下一个：YM 511上一个：Desmethyl-YM 298198 |
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