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/ Products Classification 点击展开+Cat. Number | YM 26734 |
Chemical Name | YM 26734 |
CAS Number | [144337-18-8] |
Mol. Formula | C45H62O8 |
Mol. Weight | 730.97 |
Qty 1 |
10mg |
Synonym | 1,1'-[5-[3,4-Dihydro-7-hydroxy-2-(4- hydroxyphenyl)-2H-1-benzopyran-4-yl]-2,4,6-trihydr oxy-1,3-phenylene]bis-1-dodecanone |
Solubility | Soluble to 100 mM in DMSO and to 100 mM in ethanol |
Storage condition | Store at -20°C |
References | Competitive inhibitor of secretory phospholipase A2 (sPLA2) that exhibits a broad inhibitory profile to several sPLA2s (IC50 values are 0.2, 1, 1, 1 and 3 μM for sPLA2-X, -IIA, -IID, -V and -IIE respectively). Displays minimal activity at sPLA2-IIF and no activity at cytosolic PLA2, cyclooxygenase and lipoxygenase. Ameliorates local inflammatory responses in TPA-induced mouse ear edema. Purity: >96 % |
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