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| Cat. Number | Y-27632 dihydrochloride |
| Chemical Name | Y-27632 dihydrochloride |
| CAS Number | [146986-50-7] |
| Mol. Formula | C14H21N3O.2HCl |
| Mol. Weight | 320.26 |
| Qty 1 |
1mg |
| Qty 2 | 50mg |
| Synonym | trans-4-[(1R)-1-Aminoethyl]-N-4-pyr idinylcyclohexanecarboxamide dihydrochloride |
| Solubility | Soluble to 100 mM in water |
| Storage condition | Desiccate at RT |
| References | Selective inhibitor of the Rho-associated protein kinase p160ROCK. Ki values are 0.14, 26, 25 and > 250 μM for p160ROCK, PKC, cAMP-dependent protein kinase and myosin light-chain kinase respectively. Also inhibits the protein kinase C-related protein kinase, PRK2 (IC50 = 600nM). Smooth muscle relaxant and orally active in vivo. Increases survival rate of human embryonic stem (hES) cells undergoing cryopreservation. Purity: >98 % |
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