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Cat. Number
Y 134
Chemical Name
Y 134
CAS Number
[849662-80-2]
Mol. Formula
C28H28N2O3S
Mol. Weight
472.6
Qty 1
10mg
Qty 2
50mg
Synonym
[6-Hydroxy-2-(4-hydroxyphenyl)benzo [b]thien-3-yl]-[4-[4-(1-methylethyl)-1-piperazinyl ]phenyl]methanone
Solubility
Soluble to 100 mM in DMSO and to 100 mM in ethanol
Storage condition
Desiccate at RT
References
Selective estrogen receptor modulator (SERM) that displays selectivity for ERα over ERβ (Ki values are 0.09 and 11.31 nM respectively) and no cross-reactivity with mineralocorticoid, glucocorticoid, androgen and progesterone receptors. Acts as an agonist in the bone and antagonist in reproductive tissue. Suppresses estrogen-stimulated proliferation of ER-positive human breast cancer MCF-7 and T47D cells.
Purity: >98 %
下一个:Y-25130 hydrochloride上一个:Zotepine
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