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| Cat. Number | Zoniporide dihydrochloride |
| Chemical Name | Zoniporide dihydrochloride |
| CAS Number | [241800-97-5] |
| Mol. Formula | C17H16N6O.2HCl |
| Mol. Weight | 393.27 |
| Qty 1 |
10mg |
| Qty 2 | 50mg |
| Synonym | [1-(Quinolin-5-yl)-5-cyclopropyl-1H -pyrazole-4-carbonyl]guanidine dihydrochloride |
| Solubility | Soluble to 100 mM in water and to 100 mM in DMSO |
| Storage condition | Desiccate at -20°C |
| References | Sodium-hydrogen exchanger isoform-1 (NHE-1) inhibitor that displays selectivity over other NHE isoforms (Ki values are 14, 2200 and 220000 nM for human NHE-1, human NHE-2 and rat NHE-3 respectively). Inhibits NHE-1 dependent 22Na+ uptake in vitro (IC50 = 14 nM) and provides cardioprotection from myocardial ischemic injury in vivo (EC50 = 0.25 nM). Purity: >99 % |
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