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| Cat. Number | ZM 449829 |
| Chemical Name | ZM 449829 |
| CAS Number | [4452-06-6] |
| Mol. Formula | C13H10O |
| Mol. Weight | 182.22 |
| Qty 1 |
10mg |
| Qty 2 | 50mg |
| Synonym | 1-(2-Naphthalenyl)-2-propen-1-one |
| Storage condition | Desiccate at -20°C |
| References | Potent, selective inhibitor of Janus tyrosine kinase 3 (JAK3) which binds competitively to the JAK3 ATP site. pIC50 values are 6.8, 5.0, 4.7, and < 5.0 for JAK3, EGFR, JAK1 and CDK4 respectively. Inhibits STAT-5 phosphorylation and T-cell proliferation. Purity: >98 % |
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