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| Cat. Number | ZM 447439 |
| Chemical Name | ZM 447439 |
| CAS Number | [331771-20-1] |
| Mol. Formula | C29H31N5O4 |
| Mol. Weight | 513.59 |
| Qty 1 |
10mg |
| Synonym | N-[4-[[6-Methoxy-7-[3-(4-morpholiny l)propoxy]-4-quinazolinyl]amino]phenyl]benzamide |
| Solubility | Soluble to 100 mM in DMSO |
| Storage condition | Desiccate at RT |
| References | Novel, selective ATP-competitive inhibitor of Aurora B kinase in vitro (IC50 values are 50, 250 and 1000 nM for Aurora B, C and A kinases respectively). Selective over a range of other kinases including cdk1 and PLK1 (IC50 > 10 μM). Inhibits cell division and displays selective toxicity towards proliferating tumor cells versus non-dividing cells. Purity: >99 % |
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