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| Cat. Number | ZM 336372 |
| Chemical Name | ZM 336372 |
| CAS Number | [208260-29-1] |
| Mol. Formula | C23H23N3O3 |
| Mol. Weight | 389.45 |
| Qty 1 |
10mg |
| Qty 2 | 50mg |
| Synonym | 3-(Dimethylamino)-N-[3-[(4-hydroxyb enzoyl)-amino]-4-methylphenyl]benzamide |
| Solubility | Soluble to 100 mM in DMSO |
| Storage condition | Store at +4°C |
| References | Potent, selective inhibitor of c-Raf in vitro (IC50 = 70 nM for inhibition of human c-Raf). Shows 10-fold selectivity over B-Raf. Also inhibits SAPK2/p38 (IC50 = 2 μM). Selective over 17 other protein kinases including PKA, PKC, p42 MAPK, CDK1 and SAPK1/JNK (up to 50 μM). Also available as part of the MAPK Cascade Inhibitor Tocriset™. Purity: >98 % |
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