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/ Products Classification 点击展开+Cat. Number | ZM 323881 hydrochloride |
Chemical Name | ZM 323881 hydrochloride |
CAS Number | [324077-30-7] |
Mol. Formula | C22H18FN3O2.HCl |
Mol. Weight | 411.86 |
Qty 1 |
1mg |
Qty 2 | 10mg |
Synonym | 5-((7-Benzyloxyquinazolin-4-yl)amin o)-4-fluoro-2-methylphenol hydrochloride |
Solubility | Soluble to 50 mM in DMSO |
Storage condition | Desiccate at +4°C |
References | Potent and selective inhibitor of human vascular endothelial growth factor receptor 2 (VEGFR-2/KDR) activity. Selectively inhibits VEGFR-2 (IC50 = 2 nM) over VEGFR-1 and a range of other receptor tyrosine kinases such as PDGFRβ, FGFR1, EGFR and erbB2 (IC50 > 50 μM). Inhibits VEGF-A-induced endothelial cell proliferation in vitro (IC50 = 8 nM). Purity: >99 % |
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