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| Cat. Number | ZK 200775 |
| Chemical Name | ZK 200775 |
| CAS Number | [161605-73-8] |
| Mol. Formula | C14H15N3O6F3P |
| Mol. Weight | 409.25 |
| Qty 1 |
10mg |
| Qty 2 | 50mg |
| Synonym | [[3,4-Dihydro-7-(4-morpholinyl)-2,3 -dioxo-6-(trifluoromethyl)-1(2H)-quinoxalinyl]meth yl]phosphonic acid |
| Solubility | Soluble to 100 mM in DMSO and to 50 mM in ethanol |
| Storage condition | Desiccate at +4°C |
| References | Competitive AMPA/kainate antagonist. In rat cortical membranes, displays high affinity for [3H]-AMPA (Ki = 120 nM) and [3H]-CNQX (Ki = 32 nM) binding sites and low affinity for kainate and NMDA channel-associated binding sites (IC50 values range from 2.5 to 11 μM). Inhibits currents induced by AMPA, kainate and NMDA with IC50 values of 21 nM, 27 nM, and > 1 μM respectively. Displays anxiolytic, anticonvulsant and muscle relaxant activity in vivo. Purity: >99 % |
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