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| Cat. Number | ZIP |
| Chemical Name | ZIP |
| CAS Number | [863987-12-6] |
| Mol. Formula | C90H154N30O17 |
| Mol. Weight | 1928.4 |
| Qty 1 |
1mg |
| Storage condition | Desiccate at -20°C |
| References | Novel, cell-permeable inhibitor of protein kinase Mζ (PKMζ), a constitutively active, atypical PKC isozyme involved in LTP maintenance. Selectively blocks PKMζ-induced synaptic potentiation in hippocampal slices in vitro. Reverses late-phase LTP (IC50 = 1 - 2.5 μM) and produces persistent loss of 1-day-old spatial memory following central administration in vivo. |
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