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| Cat. Number | Zileuton |
| Chemical Name | Zileuton |
| CAS Number | [111406-87-2] |
| Mol. Formula | C11H12N2O2S |
| Mol. Weight | 236.29 |
| Qty 1 |
10mg |
| Qty 2 | 50mg |
| Synonym | N-(1-Benzo[b]thien-2-ylethyl)-N-hyd roxyurea |
| Solubility | Soluble to 100 mM in DMSO |
| Storage condition | Store at +4°C |
| References | Orally active 5-lipoxygenase (5-LOX) inhibitor that inhibits LTB4 synthesis (IC50 values are 0.56, 2.3 and 2.6 μM in dog, rat and human blood respectively). Inhibits antigen-induced contraction of tracheal strips in vitro (IC50 = 6 μM) and exhibits antiasthmatic activity in vivo. Also weakly inhibits CYP1A2 (Ki = 66 - 98 μM). Purity: >99 % |
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