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Cat. Number
F5868
Chemical Name
F5868 富马酸福莫特罗 Formoterol fumarate dihydrate 43229-80-7
CAS Number
43229-80-7
Mol. Formula
(C19H24N2O4)2C4H4O4 2H2O
Mol. Weight
840.91
Qty 1
10mg
Qty 2
50mg
Synonym
Formoterol Fumarate;Atock; Foradil; Oxeze
Melting Pt.
138
References

Formoterol is a long-acting β2-adrenergic receptor agonist that is clinically used to treat asthma and chronic obstructive pulmonary disease (COPD). Formoterol exhibits bronchodilatory, anti-asthma, and anti-obesity activities. In a clinical setting, formoterol increases resting energy expenditure, fat utilization, and mitochondrial biogenesis; it also increases mitochondrial expression of NADH dehydrogenase and ATP synthase.

Lee P, Day RO, Greenfield JR, et al. Formoterol, a highly β2-selective agonist, increases energy expenditure and fat utilisation in men. Int J Obes (Lond). 2013 Apr;37(4):593-7. PMID: 22641064.

Wills LP, Trager RE, Beeson GC, et al. The β2-adrenoceptor agonist formoterol stimulates mitochondrial biogenesis. J Pharmacol Exp Ther. 2012 Jul;342(1):106-18. PMID: 22490378.

Rider CF, King EM, Holden NS, et al. Inflammatory stimuli inhibit glucocorticoid-dependent transactivation in human pulmonary epithelial cells: rescue by long-acting beta2-adrenoceptor agonists. J Pharmacol Exp Ther. 2011 Sep;338(3):860-9. PMID: 21622733.

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