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Cat. Number
HT6903
Chemical Name
盐酸苯环丙胺,Tranylcypromine Hydrochloride
CAS Number
1986-47-6
Mol. Formula
C9H11N.HCl
Mol. Weight
169.65
Qty 1
20mg/692元
Qty 2
500mg
Application Notes
≥98%
Synonym
(1R,2S)-rel-2-Phenylcyclopropylamine ; SKF-385
Melting Pt.
164-166°C
Solubility
Soluble to 100 mM in water and to 100 mM in DMSO
Storage condition
+4°C
References

Tranylcypromine hydrochloride is a cell-permeable small molecule that inhibits lysine-specific demethylase 1 (LSD1) in vivo. LSD1 is a histone demethylase capable of demethylating lysine residues 1. 
When combined with CHIR99021, an inhibitor of glycogen synthase kinase 3 (GSK3), tranylcypromine is able to generate human-induced pluripotent stem cells in the absence of the transcription factor sox2 2. Stemolecule™ Tranylcypromine hydrochloride, 
therefore, can have applications to replace transcription factors in both mouse and human cell reprogramming.

A monoamine oxidase (MAO) inhibitor. It reduces conversion of N-acetyl-1,6- diaminohexane (NAD-AH) to 6-acetamido- hexanoic acid (AcHA) catalyzed by MAO. Tranylcypromine was found to enhancie Hexmethylene bisacetamide (HMBA) and its metabolite NAD-AH indu