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Cat. Number
HA4443
Chemical Name
蒜氨酸,L(+)Alliin
CAS Number
556-27-4
Mol. Formula
C6H11NO3S
Mol. Weight
177.22
Qty 1
25mg
Qty 2
100mg
Application Notes
≥98%
Synonym
3-(2-Propenylsulfinyl) alanine

3-[(S)-2-Propenylsulfinyl]-L-alanine

S-Allyl-L-cysteine sulfoxide 3-(Allylsulfinyl)alanin Alliin EINECS 209-118-9 S-Allyl-L-cystein-S-oxid

Melting Pt.
164-166°C
Solubility
Soluble in water. Insoluble in ethanol, or acetone
Storage condition
-20℃
References

L-(+)-Alliin is a cysteine derivative isolated from Allium; it exhibits anti-inflammatory, neuromodulatory, anti-diabetic, anti-hyperlipidemic, antioxidative, cardioprotective, and anti-angiogenic activities; it is the optically active and orally bioavailable isomer of alliin. In adipocytes, L-alliin inhibits LPS-stimulated activation of ERK1/2 and increases in inflammatory signaling. In animal models of myocardial infarction, L-alliin increases activity of superoxide dismutase, glutathione peroxidase, catalase, and glutathione-S-transferase. L-Alliin also activates NMDA-R subunits NR2A and NR2B. In diabetic rats, this compound decreases levels of LDL, VLDL, glucose, triglycerides, total cholesterol, and total lipids. Additionally, L-alliin inhibits VEGF-induced angiogenesis and FGF2 and VEGF secretion in fibrosarcoma cells.

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