A member of the camptothecin drug family, and an inhibitor of the nuclear enzyme topoisomerase I, which is involved in cellular DNA replication and transcription. During replication topoisomerase I mediates the relaxation of super coiled DNA, and its inhibition results in breakage of the DNA chain and likely induce apoptosis. Irinotecan is, therefore, an attractive target for anticancer drug development. Currently it is used for the treatment of small cell lung cancer and advanced colorectal cancer.
[Camptosar, 7-ethyl-10-hydroxycamptothecin, CPT-11]
Irinotecan 上海 >10 现货库存
Purity: ≥98% (HPLC)
规 格：100mg / 瓶 1920 RMB
其它名称:
Irinotecan Hydrochloride, S-Form
Irinotecan, Hydrochloride
[1,4'-Bipiperidine]-1'-carboxylic acid, (4S)-4,11-diethyl-3,4,12,14-tetrahydro-4-hydroxy-3,14-dioxo-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinolin-9-yl ester, monohydrochloride (9CI)
1H-Pyrano[3',4':6,7]indolizino[1,2- b]quinoline, [1,4'-bipiperidine]-1'-carboxylic acid deriv
(S)-([1,4'-Bipiperidine]-1'-carboxylic acid, 4,11-diethyl-3,4,12,14-tetrahydro-4-hydroxy-3,14-dioxo-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinolin-9-yl ester, monohydrochloride, (S)-)
(7-Ethyl- 10-[[4-(1-piperidyl)-1-piperidyl]carbonyloxy]camptothecin hydrochloride)
([1,4'-Bipiperidine]-1'-carboxylic acid, (4S)-4,11-diethyl-3,4,12,14-tetrahydro-4-hydroxy-3,14-dioxo-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinolin-9-yl ester, hydrochloride (1:1))
U 101440E
Topotecin hydrochloride
Camptosar
Irinotecan
7-Ethyl-10-(4-(1-piperidino)-1-piperidino)carbonyloxycamptothecin
Camptothecin-11
(1,4'-Bipiperidine)-1'-carboxylic acid, 3,4,12,14-tetrahydro-4,11-diethyl-4-hydroxy-3,4-dioxo-1H-pyrano(3',4':6,7)indolizino(1,2-b)quinolin-9-yl ester, monohydrochloride, (S)-
Campto
Camptothecin 11 hydrochloride
CPT 11
7-Ethyl-10-(4-(1-piperidino)-1-piperidino)carbonyloxycamptothecin hydrochloride
Irinotecan hydrochloride
Topotecin
U 10144OE
