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Cat. Number
733987599819630
Chemical Name
Y-27632
CAS Number
331752-47-7
Category
Inhibitors, Pharmaceuticals, Intermediates & Fine Chemicals, Protein Kinase Inhibitors and Activators,
Mol. Formula
C14H25Cl2N3O2
Mol. Weight
338.27
Qty 1
5mg
Qty 2
50mg
Appearance
White Solid
Application Notes
A Rho kinase inhibitor (ROCK) for the treatment of ischemia-reperfusion disorders.
Synonym
trans-4-[(1R)-1-Aminoethyl]-N-4-pyridinyl-cyclohexanecarboxamide Dihydrochloride Monohydrate; (R)-(+)-trans-4-(1-Aminoethyl)-N-(4-pyridyl)cyclohexanecarboxamide Dihydrochloride Monohydrate;
Melting Pt.
N/A
Solubility
Methanol
Storage condition
Refrigerator, Under Inert Atmosphere
Stability
Hygroscopic; Light Sensitive;
References
Hirose, M., et al.: J. Cell. Biol., 141, 1625 (1998), Maekawa, M., et al.: Science, 285, 895 (1999), Ye, X., et al.: Jpn. J. Pharmacol., 83, 161 (2000), Chitaley, et al.: Nat. Med., 7, 119 (2001), Watanabe, K., et al.: Nature Biotech., 25, 681 (2007),
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