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Cat. Number
733987723831306
Chemical Name
Verapamil Ethyl Methanethiosulfonate, Bromide
CAS Number
353270-25-4
Category
MTS & Sulfhydryl Active Reagents, Pharmaceuticals, Intermediates & Fine Chemicals,
Mol. Formula
C30H45BrN2O6S2
Mol. Weight
673.72
Qty 1
5mg
Qty 2
50mg
Appearance
White Powder
Application Notes
An analog of Verapamil. P Glycoprotein drug binding domain verapamil methanethiosulfonate. Useful for mapping the pore region of L-type calcium channels and Kv1.3 potassium channels.
Synonym
δ-Cyano-N-[2-(3,4-dimethoxyphenyl)ethyl]-3,4-dimethoxy-N-methyl-δ-(1-methylethyl)-N-[2-[(methylsulfonyl)thio]ethyl]benzenebutanaminium Bromide;
Melting Pt.
105-110°C (foaming)
Solubility
Dichloromethane, DMSO, Methanol
Storage condition
Amber Vial, Refrigerator, Under Inert Atmosphere
References
Loo, T., et al.: J. Biol. Chem., 270, 843 (1995), Sharom, F., et al.: J. Membr. Biol., 160, 161 (1997), Kim, R., et al.: J. Clin. Invest., 101, 289 (1998), Lee, C., et al.: Biochemistry., 37, 3594 (1998),
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