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Cat. Number
733987783385965
Chemical Name
Tyrphostin 25
CAS Number
118409-58-8
Category
Inhibitors; Tyrosine Kinase Inhibitors
Mol. Formula
C10H6N2O3
Mol. Weight
202.30
Qty 1
25mg
Qty 2
250mg
Appearance
Yellow Green Powder
Application Notes
An inhibitor of epidermal growth factor receptor tyrosine kinase activity and has a reported IC50 of 15 ?M for the autophosphorylation of the EGF-receptor.
Synonym
([3,4,5-Trihydroxybenzylidene]malononitrile)
Melting Pt.
~220°C dec.
Solubility
Acetone, Chloroform, Dichloromethane, DMF, DMSO, Methanol,
Stability
Light Sensitive
References
Gazit, A., et al.: J. Med. Chem., 32, 2344 (1989)
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