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Cat. Number
733987747431765
Chemical Name
S-Trityl-L-cysteine
CAS Number
2799-07-7
Category
Amino Acids & Derivatives, Aromatics, Chiral Reagents, Enzyme substrates
Mol. Formula
C22H21NO2S
Mol. Weight
363.47
Qty 1
100mg
Qty 2
1g
Appearance
White Solid
Application Notes
A protected cysteine for peptide synthesis. S-Trityl-L-cysteine (STLC) is a tight-binding inhibitor of Eg5 that prevents mitotic progression. It has proven antitumor activity as shown in the NCI 60 tumor cell line screen.
Synonym
S-(Triphenylmethyl)-L-cysteine; (2R)-2-Amino-3-[(triphenylmethyl)thio]propanoic Acid; 3-Tritylthio-L-alanine; NSC 83265; S-Triphenylmethyl-L-cysteine; S-Trityl-(R)-cysteine; S-Tritylcysteine; Tritylthioalanine;
Melting Pt.
>180?C (dec.)
Solubility
DMSO
Storage condition
-20?C Freezer
References
Brier, S., et al.: Biochemistry, 43, 13072 (2004), Sakowicz, R., et al.: Cancer Res., 64, 3276 (2004), Zhu, C., et al.: Mol. Biol. Cell, 16, 3187 (2005),
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