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Cat. Number
733986224279861
Chemical Name
Topotecan-d6 Carboxylic Acid Sodium Salt
Category
Chiral Reagents, Inhibitors, Isotope Labelled Compounds, Metabolites & Impurities, Pharmaceuticals, Intermediates & Fine Chemicals,
Mol. Formula
C23H18D6N3NaO6
Mol. Weight
467.48
Qty 1
1mg
Qty 2
10mg
Application Notes
The novel labelled carboxylate metabolite of Topotecan.
Synonym
1-[(Dimethylamino-d6)methyl]-α-ethyl-9,11-dihydro-α,2-dihydroxy-8-(hydroxymethyl)-9-oxo-indolizino[1,2-b]quinoline-7-acetic Acid Monosodium Salt;
References
Liu, L., et al.: Annu. Rev. Biochem., 58, 351 (1989), Underberg, W., et al.: J. Pharm. Biomed. Anal., 8, 681 (1990), Grochow, L., et al.: Drug Metab. Dispos., 20, 706 (1992), Scott, D., et al.: Pharm. Res., 10, 1451 (1993),
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