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/ Products Classification 点击展开+Cat. Number | 733986919024279 |
Chemical Name | Topotecan-d6 |
Category | Inhibitors, Isotope Labelled Compounds, Pharmaceuticals, Intermediates & Fine Chemicals, |
Mol. Formula | C23H17D6N3O5 |
Mol. Weight | 427.48 |
Qty 1 |
1mg |
Qty 2 | 10mg |
Appearance | Yellow Solid |
Application Notes | Labelled Topotecan. A DNA topoisomerase I inhibitor; semisynthetic analog of Camptothecin. Antineoplastic. |
Synonym | (4S)-10-[(Dimethylamino-d6)methyl]-4-ethyl-4,9-dihydroxy-1H-pyrano[3’,4’,6-7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione; NSC-609669-d6; SKF-104864A-d6; Hycamtin-d6; |
Melting Pt. | 213-218°C (dec) |
Solubility | Water |
Storage condition | -20?C Freezer |
References | Beijnen, J.H., et al.: J. Pharm. Biomed. Anal., 8, 789 (1990), BeiKingsburg, W.D., et al.: J. Med. Chem., 34, 98 (1991), Rowinsky, E.K., et al.: J. Clin. Oncol., 10, 647 (1992), |