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Cat. Number
733986419267928
Chemical Name
(5R-cis)-Toluene-4-sulfonic Acid 5-(2,4-Difluorophenyl)-5-[1,2,4]triazol- 1-ylmethyltetrahydrofuran-3-ylmethyl Ester
CAS Number
149809-43-8
Category
Aromatics, Chiral Reagents, Intermediates, Pharmaceuticals, Intermediates & Fine Chemicals
Mol. Formula
C21H21F2N3O4S
Mol. Weight
449.47
Qty 1
10mg
Qty 2
100mg
Appearance
White Crystalline Solid
Application Notes
Posaconazole intermediate. Antifungal agent.
Synonym
2,5-Anhydro-1,3,4-trideoxy-2-C-(2,4-difluorophenyl)-4-[[[(4-methylphenyl)sulfonyl]oxy]methyl]-1-(1H-1,2,4-triazol-1-yl)-D-threo-pentitol;
Melting Pt.
100-102°C
Solubility
Chloroform
Storage condition
-20?C Freezer, Under Inert Atmosphere
References
Ator, M., et al.: J. Med. Chem., 35, 100 (1992), Andriole, V., et al.: J. Antimicrob. Chemother., 44, 151 (1999), Beuchet, P., et al.: Bioorg. Med. Chem., 9, 1599 (1999),
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