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Cat. Number
733985612410839
Chemical Name
D-erythro-Sphingosine
CAS Number
123-78-4
Category
Amines, Glycerols, Fatty Acid Derivatives & Lipids, Inhibitors, Protein Kinase Inhibitors and Activators
Mol. Formula
C18H37NO2
Mol. Weight
299.49
Qty 1
25mg
Qty 2
250mg
Appearance
White Crystalline Solid
Application Notes
Selective inhibitor of protein kinase C activity and phorbol dibutyrate binding in vitro in human platelets; does not inhibit protein kinase A or myosin light chain kinase; inhibits calmodulin-dependent enzymes; natural isomer of sphingosine.
Synonym
2-Amino-4-octadecene-1,3-diol; trans-4-Sphingenine; Erythrosphingosine; (2S,3R,4E)-2-Amino-4-octadecene-1,3-diol; (-)-Sphingosine;
Melting Pt.
68-70°C
Solubility
Chloroform, Methanol
Stability
Store in freezer
References
Yoon, C., et al.: Mol. Cancer Res., 7, 361 (2009), Giussani, P., et al.: J. Biol. Chem., 284, 5088 (2009), Chen-Quay, S., et al.: J. Pharm. Sci., 98, 606 (2009), Satoh, Y., et al.: J. Biochem., 145, 31 (2009),
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