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/ Products Classification 点击展开+| Cat. Number | 733985929170764 |
| Chemical Name | SN-38 Carboxylate Disodium Salt
|
| Category | Chiral Reagents, Metabolites & Impurities, Pharmaceuticals, Intermediates & Fine Chemicals, |
| Mol. Formula | C22H20N2Na2O6 |
| Mol. Weight | 454.38 |
| Qty 1 |
1mg |
| Qty 2 | 10mg |
| Appearance | Yellow Solid |
| Application Notes | The active metabolite of Irinotecan (carboxylate form). SN-38 lactone and carboxylate may be considered pharmacokinetically distinct agents. |
| Synonym | (αS)- α,12-Diethyl-9,11-dihydro-α,2-dihydroxy-8-(hydroxymethyl)-9-oxo- 9-indolizino[1,2-b]quinoline-7-acetic Acid Disodium Salt; SN 38 Acid Sodium Salt;
|
| Melting Pt. | >220°C (dec.) |
| Solubility | DMSO, Methanol, Water |
| Storage condition | Hygroscopic, -20?C Freezer, Under Inert Atmosphere |
| References | Billecke, S., et al.: Drug Metab. Dispos., 28, 1335 (2000), Teiber, J., et al.: Biochem. Pharmacol., 66, 887 (2003), Ashley, G., et al.: J. Antibiot., 57, 224 (2004), |
下一个：SN-38 4-Deoxy-glucuronide上一个：S589952 |
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