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Cat. Number
733985630230914
Chemical Name
SN-38-d3
CAS Number
718612-49-8
Category
Chiral Reagents, Isotope Labelled Compounds, Metabolites & Impurities, Pharmaceuticals, Intermediates & Fine Chemicals,
Mol. Formula
C22H17D3N2O5
Mol. Weight
395.42
Qty 1
1mg
Qty 2
10mg
Appearance
Light-Yellow Solid
Application Notes
Labelled SN-38, a metabolite of Irinotecan, a DNA topoisomerase inhibitor.
Synonym
(4S)-4-Ethyl-11-(ethyl-d3)-4,9-dihydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione; 7-Ethyl-10-hydroxycamptothecin-d3; 10-Hydroxy-7-ethylcamptothecin-d3; SN 38-d3 Lactone;
Solubility
Dimethyl Sulfoxide
References
Billecke, S., et al.: Drug Metab. Dispos., 28, 1335 (2000), Teiber, J., et al.: Biochem. Pharmacol., 66, 887 (2003), Ashley, G., et al.: J. Antibiot., 57, 224 (2004),
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