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Cat. Number
733985863243488
Chemical Name
SN-38
CAS Number
86639-52-3
Category
Chiral Reagents, Metabolites & Impurities, Pharmaceuticals, Intermediates & Fine Chemicals,
Mol. Formula
C22H20N2O5
Mol. Weight
392.40
Qty 1
5mg
Qty 2
50mg
Appearance
Light-Yellow Solid
Application Notes
A metabolite of Irinotecan, a DNA topoisomerase inhibitor.
Synonym
(4S)-4,11-Diethyl-4,9-dihydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)dione; 7-Ethyl-10-hydroxycamptothecin; 10-Hydroxy-7-ethylcamptothecin; SN 38 Lactone;
Melting Pt.
218-221°C dec.
Solubility
Dimethyl Sulfoxide
Storage condition
-20?C Freezer
References
Billecke, S., et al.: Drug Metab. Dispos., 28, 1335 (2000), Teiber, J., et al.: Biochem. Pharmacol., 66, 887 (2003), Ashley, G., et al.: J. Antibiot., 57, 224 (2004),
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