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Cat. Number
733985949882359
Chemical Name
Sitaxsentan Sodium
CAS Number
210421-74-2
Category
Heterocycles, Pharmaceuticals, Intermediates & Fine Chemicals, Sulfur & Selenium Compounds
Mol. Formula
C18H14ClN2NaO6S2
Mol. Weight
476.89
Qty 1
10mg
Qty 2
25mg
Application Notes
Selective endothelin A (ETA) receptor antagonist. Antihypertensive. Used in treatment of chronic heart failure.
Synonym
N-(4-Chloro-3-methyl-5-isoxazolyl)-2-[2-(6-methyl-1,3-benzodioxol-5-yl)acetyl]-3-thiophenesulfonamide Sodium; IPI 1040; Sitax; Sitaxentan Sodium; TBC 11251; Thelin;
References

 

Wu, C., et al.: J. Med. Chem., 40, 1690 (1997),
Tilton, R.G., et al.: Pulm. Pharmacol. Ther., 13, 87 (2000),
Horn, E.M., et al.: Expert. Opin. Invest. Drugs, 13, 1483 (2004),
Langleben, D., et al.: Chest, 126, 1377 (2004),

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