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Cat. Number
733985358217409
Chemical Name
SEW 2871
CAS Number
256414-75-2
Category
Heterocycles, Pharmaceuticals, Intermediates & Fine Chemicals, Sulfur & Selenium Compounds
Mol. Formula
C20H10F6N2OS
Mol. Weight
440.36
Qty 1
5mg
Qty 2
50mg
Application Notes
Novel, selective human Sphingosine-1-phosphate subtype 1 (S1P1) receptor agonist. It is used as medicament for treating and/or preventing cardiovascular conditions in patients with Fabry disease.
Synonym
5-[4-Phenyl-5-(trifluoromethyl)-2-thienyl]-3-[3-(trifluoromethyl)phenyl]-1,2,4-oxadiazole;
References
Dudek, S., et al.: J. Biol. Chem., 279, 24692 (2004), Alfonso, C., et al.: Eur. J .Immunol., 36, 149 (2006), Cherezov, V., et al.: Science, Weinreich, M., et al.: J. Immunol., 181, 2265 (2008),
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