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/ Products Classification 点击展开+| Cat. Number | 733984437484414 |
| Chemical Name | Panobinostat |
| CAS Number | 404950-80-7 |
| Category | Aromatics, Heterocycles, Inhibitors, Pharmaceuticals, Intermediates & Fine Chemicals, |
| Mol. Formula | C21H23N3O2 |
| Mol. Weight | 349.43 |
| Qty 1 |
2.5mg |
| Qty 2 | 25mg |
| Appearance | Yellow Solid |
| Application Notes | The novel histone deacetylase inhibitor, LBH589, induces expression of DNA damage response genes and apoptosis in Ph- acute lymphoblastic leukemia cells. |
| Synonym | (2E)- N-Hydroxy-3-[4-[[[2-(2-methyl-1H-indol-3-yl)ethyl]amino]methyl]phenyl]- 2-propenamide ; LBH 589; |
| Melting Pt. | 114-117?C |
| Solubility | DMSO, Methanol |
| Storage condition | -20?C Freezer, Under Inert Atmosphere |
| References | Claus, R., et al.: Oncogene, 22, 6489 (2003), Johnstone, R., et al.: Cancer Cell., 4, 13 (2003), Ying, J., et al.: Clin. Cancer Res., 11, 6442 (2005), Catley, L., et al.: Blood, 108, 3441 (2006), Steinberg, M., et al.: Clin. Ther., 29, 2289 (2007), |
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