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/ Products Classification 点击展开+| Cat. Number | 733984882659700 |
| Chemical Name | Pamapimod |
| CAS Number | 449811-01-2 |
| Category | Amines, Aromatics, Heterocycles, Pharmaceuticals, Intermediates & Fine Chemicals |
| Mol. Formula | C19H20F2N4O4 |
| Mol. Weight | 406.38 |
| Qty 1 |
25mg |
| Application Notes | A selective inhibitor of the α-isoform of p38 MAP kinase . It is used in in treatment of patient with rheumatoid arthritis . Pamapimod was tolerable but not effective as Methotrexate . |
| Synonym | 6-(2,4-Difluorophenoxy)-2-[[3-hydroxy-1-(2-hydroxyethyl)propyl]amino]-8-methylpyrido[2,3-d]pyrimidin-7(8H)-one; R 1503; Ro 4402257; |
| References | Guan, Z., et al.: J. Biol. Chem., 273, 12901 (1998), Lee, J., et al.: Pharmacol. Ther., 82, 389 (1999), Korb, A., et al.: Arthritis Rheum., 54, 2745 (2006), |
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