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Cat. Number
733983593145473
Chemical Name
3-Oxo-4-aza-5α-αndrost-1-ene-17β-carboxylic Acid
CAS Number
104239-97-6
Category
Intermediates, Pharmaceuticals, Intermediates & Fine Chemicals, Steroids
Mol. Formula
C19H27NO3
Mol. Weight
317.42
Qty 1
25mg
Qty 2
250mg
Appearance
Off-White Powder
Application Notes
A novel intermediate in the synthesis of Finasteride, a 5α-reductase inhibitor used for treatment of benign prostatic hyperplasia acne, seborrhea, female hirsutism, prostatitis, and prostatic carcinoma and other hyperandrogenetic related disorders.
Synonym
(4aR,4bS,6aS,7S,9aS,9bS,11aR)-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-4a,6a-dimethyl-2-oxo-1H-indeno[5,4-f]quinoline-7-carboxylic Acid Methyl Ester; (5α,17β)-3-oxo-4-Azaandrost-1-ene-17-carboxylic Acid Methyl Ester;
Melting Pt.
320-322°C
Solubility
Chloroform, DMSO, Methanol, n-Propanol
References
Bakshi., et al.: J. Med. Chem., 38, 3189 (1995),
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