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Cat. Number
733983314333665
Chemical Name
Nortilidine-d3 Hydrochloride
Category
Amines, Aromatics, Isotope Labelled Compounds, Metabolites & Impurities, Pharmaceuticals, Intermediates & Fine Chemicals
Mol. Formula
C16H19D3ClNO2
Mol. Weight
298.82
Qty 1
1mg
Qty 2
10mg
Appearance
Off-White Solid
Application Notes
The labelled active metabolite of Tilidine. A receptor antagonist. Nortilidine easily penetrates the blood-brain barrier and activates the ?-opioid receptor. The enzymes involved in Tilidine metabolism are unknown.
Synonym
trans-2-(Methyl-d3)amino-1-phenyl-3-cyclohexene-1-carboxylic Acid Ethyl Ester Hydrochloride;
Melting Pt.
208-210?C
Solubility
Chloroform, Methanol, Water
Storage condition
Refrigerator
References
Boesch, D., et al.: Cancer Res., 51, 4226 (1991), Austin, R., et al.: Drug Metab. Dispos., 30, 1497 (2002), Hajda, J., et al.: J. Clin. Pharmacol., 42, 1257 (2002), Thierry, C., et al.: Eur. J. Pharmacol., 506, 205 (2005),
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