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/ Products Classification 点击展开+| Cat. Number | 733982913153383 |
| Chemical Name | MLN 4924 |
| CAS Number | 905579-51-3 |
| Category | Carbohydrates & Derivatives, Heterocycles, Inhibitors, Nucleotides, Bases & Related Reagents, Pharmaceuticals, Intermediates & Fine Chemicals, |
| Mol. Formula | C21H25N5O4S |
| Mol. Weight | 443.52 |
| Qty 1 |
10mg |
| Application Notes | A potent and selective inhibitor of NAE. An inhibitor of NEDD8-activating enzyme as a new approach to treat cancer�. The ubiquitin-proteasome pathway mediates the destruction of unwanted proteins. |
| Synonym | Sulfamic Acid [(1S,2S,4R)-4-[4-[[(1S)-2,3-dihydro-1H-inden-1-yl]amino]-7H-pyrrolo[2,3-d]pyrimidin-7-yl]-2-hydroxycyclopentyl]methyl Ester; � |
| References | Haas, A., et al.: J. Biol. Chem., 257, 10329(1982), Walden, H., et al.: Nature, 422, 330 (2003), Kane, R., et al.: Clin. Cancer Res., 13, 5291 (2007),Saha, A., et al.: Mol. Cell., 32, 21 (2008), |
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