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Cat. Number
733981180727513
Chemical Name
Methyl 2,5-Dihydroxycinnamate
CAS Number
63177-57-1
Category
Inhibitors; Tyrosine Kinase Inhibitors
Mol. Formula
C10H10O4
Mol. Weight
194.20
Qty 1
25mg
Qty 2
250mg
Appearance
Pale Yellow Solid
Application Notes
A stable Erbstatin analogue that inhibits tyrosine kinase. Shown to delay the S-phase induction by epidermal growth factor in quiescent normal rat kidney cells, without affecting the total amount of DNA synthesis.
Synonym
3-(2,5-Dihydroxyphenyl)-2-propenoic Acid Methyl Ester;
Melting Pt.
178-180°C
Solubility
Methanol
Storage condition
-20?C Freezer
References
Zheng, J., et al.: Br. J. Pharmacol., 130, 1115 (2000), Zhou, G., et al.: J. Clin. Invest., 108, 1167 (2001), Reznick, R., et al.: J. Physiol., 574, 33 (2000),
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