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Cat. Number
733980109653823
Chemical Name
Methioprim
CAS Number
588-36-3
Category
Amines, Aromatics, Heterocycles, Sulfur & Selenium Compounds
Mol. Formula
C6H9N3OS
Mol. Weight
171.22
Qty 1
10mg
Qty 2
100mg
Application Notes
An intermediate used in the synthesis of Thiamine (T344185). Also, used for the preparation of pyridopyrimidines and naphthyridines as inhibitors of Akt kinase for the treatment of cancer.
Synonym
4-Amino-2-methylthio-5-pyrimidinemethanol; (4-Amino-2-methanethiopyrimidin-5-yl) methanol; 2-Methylmercapto-4-amino-5-hydroxymethylpyrimidine; 4-Amino-2- methylmercapto-5-pyrimidinemethanol; NSC 3431; NSC 43811;
References
Zinda, M., et al.: Clin. Cancer Res., 7, 2475 (2001), Breitenlechner, C., et al.: J. Med. Chem., 47, 1375 (2004), Zhao, Z., et al.: Bioorg. Med. Chem. Lett., 18, 49 (2008),
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