L-蛋氨酸亚砜酰亚胺 L-Methionine-Sulfoximine_上海惠诚生物生物试剂,标准品,仪器设备,耗材,一站式服务

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Cat. Number

HA11621

Chemical Name

L-蛋氨酸亚砜酰亚胺 L-Methionine-Sulfoximine

CAS Number

15985-39-4

Category

Amino Acids & Derivatives

Mol. Formula

C5H12N2O3S

Mol. Weight

180.23

Qty 1

Qty 2

10g

Appearance

White Crystalline Powder

Synonym

L-S-[3-Amino-3-carboxypropyl]-S-methyl-[R,S]-sulfoximine; (2S)-2-Amino-4-(S-methylsulfonimidoyl)butanoic Acid;

Melting Pt.

>210°C

Solubility

Water

Storage condition

-20°C Freezer

Stability

Temperature Sensitive

References

L-甲硫氨酸亚砜亚胺是通过L-甲硫氨酸氧化而来的一种产物，分子式为C5H11NO3S，相对分子质量为163.21。其中L-甲硫氨酸的硫氧原子被氧化为亚砜基团(-SO-)，而α-氨基被脱落得到亚胺基。L-甲硫氨酸亚砜亚胺与机体的硫代葡萄糖酸代谢、氧化应激状态密切相关。L-甲硫氨酸亚砜亚胺已被用作谷氨酰胺合成酶（GS）活性的一种有效抑制剂。L-甲硫氨酸亚砜可抑制谷氨酰胺合成酶和g-谷氨酰半胱氨酸合成酶。抑制g-谷氨酰基半胱氨酸合成酶的工作浓度为0.2-2.0 mM (100 mM时抑制率为52%)。

订购信息:

产品名称	纯度	规格
L-甲硫氨酸亚砜亚胺	>95%	1g
L-甲硫氨酸亚砜亚胺	>95%	10g

产品信息：

CAS RN	15985-39-4
Product Name	L-甲硫氨酸亚砜亚胺 L-Methionine sulfoximine
Molecular Formula	C5H12N2O3S
Molecular Weight	180.23 g/mol
IUPAC Name	(2S)-2-amino-4-(methylsulfonimidoyl)butanoic acid
InChI	InChI=1S/C5H12N2O3S/c1-11(7,10)3-2-4(6)5(8)9/h4,7H,2-3,6H2,1H3,(H,8,9)/t4-,11?/m0/s1
InChI Key	SXTAYKAGBXMACB-DPVSGNNYSA-N
Isomeric SMILES	CS(=N)(=O)CC[C@@H](C(=O)[O-])[NH3+]
SMILES	CS(=N)(=O)CCC(C(=O)O)N
Canonical SMILES	CS(=N)(=O)CCC(C(=O)[O-])[NH3+]
Appearance	Solid powder
Other CAS RN	15985-39-4
Pictograms	Irritant
Purity	>95% (or refer to the Certificate of Analysis)
Shelf Life	>3 years if stored properly
Solubility	Soluble in DMSO
Storage	Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Synonyms	L-Methionine-(S,R)-Sulfoximine