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Cat. Number
733980163235736
Chemical Name
Mesna-d4 (contain disulfide)
CAS Number
1189479-73-9
Category
Aliphatics, Isotope Labelled Compounds, Sulfur & Selenium Compounds
Mol. Formula
C2HD4NaO3S2
Mol. Weight
168.20
Qty 1
5mg
Qty 2
50mg
Appearance
White to Off-White Solid
Application Notes
Mesna reacts with acrolein and other urotoxic metabolites of oxazaphosphorines (cyclophosphamide or ifosfamide) to form stable, non-urotoxic compounds. Mesna does not have any antitumour activity, nor does it appear to interfere with the antitumour activity of antineoplastic drugs. This medication is used to protect the bladder wall from the harmful effects of some cancer-fighting drugs.
Synonym
2-Mercaptoethanesulfonic-d4 Acid Sodium Salt; 2-Mercapto-1-ethanesulfonic-d4 Acid Monosodium Salt; D 7093-d4; Mesnex-d4; Mistabron-d4; Mistabronco-d4; Mucofluid-d4; Sodium 2-Mercaptoethanesulfonate-d4; UCB 3983-d4; Uromitexan-d4
Melting Pt.
>200°C
Boiling Pt.
N/A
Solubility
DMSO (Slightly), Water (Slightly)
Stability
Unstable in solution
References

Tekeres, M., et al.: Clin. Ther., 4, 56 (1981), Brock, N., et al.: Eur. J. Cancer Clin Oncol., 18, 1377 (1982), James, C.A., et al.: Br. J. Clin. Pharmacol., 23, 561 (1987), Schoenike, S.E., et al.: Clin. Pharm., 9, 179 (1990),

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