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Cat. Number
733980635713334
Chemical Name
(R)-Lofexidine
CAS Number
81447-78-1
Category
Aromatics, Heterocycles, Chiral Reagents, Pharmaceuticals, Intermediates & Fine Chemicals,
Mol. Formula
C11H12Cl2N2O
Mol. Weight
259.13
Qty 1
1mg
Qty 2
10mg
Application Notes
The R-enantiomer of Lofexidine. α2-Adrenoceptor agonist related structurally to Clonidine. Used in treatment of opioid withdrawal symptoms; antihypertensive.
Synonym
2-[(1R)-1-(2,6-Dichlorophenoxy)ethyl]-4,5-dihydro-1H-imidazole; (-)-Lofexidine; Levlofexidine;
References
Velly, J., et al.: J. Pharmacol., 8, 351 (1977), Jarrot, B., et al.: Biochem. Pharmacol., 28, 141 (1979), Birch, P., at al.: Brit. J. Pharmacol., 68, 107 (1980),
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