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/ Products Classification 点击展开+| Cat. Number | 733980988002057 |
| Chemical Name | (+/-)-Lisofylline |
| CAS Number | 6493-06-7 |
| Category | Metabolites & Impurities, Pharmaceuticals, Intermediates & Fine Chemicals, |
| Mol. Formula | C13H20N4O3 |
| Mol. Weight | 280.32 |
| Qty 1 |
25mg |
| Qty 2 | 250mg |
| Appearance | White Solid |
| Application Notes | A major oxidative metabolite of Pentoxifylline. A potent inhibitor of phosphatidic acid generation (IC50=0.6uM). Protects mice from endotoxic shock and attenuates sepsis-induced acute lung injury in pig. |
| Synonym | 3,7-Dihydro-1-(5-hydroxyhexyl)-3,7-dimethyl- 1H-purine-2,6-dione ; 1-(5-Hydroxyhexyl)theobromine ; (+/-)-1-(5-Hydroxyhexyl)-3,7-dimethylxanthine; BL 194; Pentoxifylline Alcohol ; |
| Melting Pt. | 123-125°C |
| Solubility | DMSO, Methanol |
| Storage condition | Refrigerator |
| References | Clarke, E., et al.: Cancer Res., et al.: 56, 105 (1996), Itani, S., et al.: Metabolism, 50, 553 (2001), Itani, S., et al.: Diabetes, 51, 2005
(2002), Yu, C., et al.: J. Biol. Chem., 277, 50230 (2002), |
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