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Cat. Number
733979977740354
Chemical Name
Indomethacin
CAS Number
53-86-1
Category
Inhibitors, Pharmaceuticals, Intermediates & Fine Chemicals,
Mol. Formula
C19H16ClNO4
Mol. Weight
357.79
Qty 1
10g
Qty 2
100g
Appearance
Crystalline Solid
Application Notes
Inhibits cyclooxygenase (IC50=0.1uM) selectively over liposygenases (IC50=100uM for 5-,12- and 15-LO). A clinically useful NAISD.
Synonym
1-(4-Chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetic Acid;
Melting Pt.
155°C Polymorphism
Solubility
Acetone, Ethanol, Ether,
Storage condition
-20?C Freezer
References
Salari, H., et al.: Prostagland. Leukotrienes Med., 13, 53 (1984), Lehmann, J.M., et al.: J. Biol. Chem., 272, 3406 (1997)
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